产品详情 |
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Antigenic Specificity | Corynebacterium diphtheriae Toxin |
Clone | 17.6 |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1, kappa |
Format | purified |
Size | 200 µl |
Concentration | n/a |
Applications | ELISA: 1:35,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Corynebacterium diphtheriae Toxin Monoclonal Antibody (17.6). Diphtheria toxin (DT) is secreted by certain strains of Corynebacterium diphtheriae and catalyzes the ADP-ribosylation of eukaryotic aminoacyl-transferase II (EF-2) using NAD as a substrate. This reaction forms the basis for its toxicity toward eukaryotic organisms. Diphtheria toxin is synthesized and excreted as a proenzyme, composed of a single polypeptide chain having a molecular weight of approximately 63 kDa. Two covalent alterations in structure are necessary for expression of its enzymatic activity. First, mild proteolysis results in the formation of nicked toxin, which is enzymatically inactive and consists of two major fragments, A and B, linked by a disulfide bond. Re |
Immunogen | n/a |
Other Names | C. diphtheriae; Diphtheria |
Gene, Accession # | n/a |
Catalog # | HYB 123-05-02 |
Price | |
Order / More Info | Corynebacterium diphtheriae Toxin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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