| 产品详情 |
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| Antigenic Specificity | COX1 |
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| Clone | COX 111 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, ovine, rat |
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| Isotype | IgG2b, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Flow Cytometry: 3-5 µg/1x10^6 cells, Immunocytochemistry: 2 µg/mL, Immunofluorescence: Assay Dependent, Immunohistochemistry: Assay Dependent, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | COX1 Monoclonal Antibody (COX 111). Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant |
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| Immunogen | n/a |
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| Other Names | COX3, PCOX1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS, COX-1, PGH synthase 1, PHS 1, cyclooxygenase-1, prostaglandin G/H synthase 1, prostaglandin H2 synthase 1 |
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| Gene, Accession # | Entrez: 19224, 24693, 443551, 5742; Uniprot: P05979, P22437, P23219, Q63921 |
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| Catalog # | 35-8100 |
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| Price | |
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| Order / More Info | COX1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 17577330, 20818651, 21536655, 21897859, 21897959, 22333315, 23222413, 23317244, 25548276, 27775717 |
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