产品详情 |
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Antigenic Specificity | COX2 |
Clone | AS73 |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | COX2 Monoclonal Antibody (AS73). Cyclooxygenase (COX), also known as prostaglandin H2 synthase and Prostaglandin endoperoxide synthase, is a key enzyme in the conversion of arachidonic acid to Prostaglandin H2. Prostaglandin H2 is converted by other enzymes into inflammatory mediators prostaglandin (PG) D2, PGE2, PGF2a, PGI2 and Thromboxane A2. Thus, COX is a key enzyme in the production of inflammatory agents and is the target of intense research and drug discovery activities. There are two enzymes of COX, COX-1, and COX-2. COX-1 is constitutively produced in many (most) cell types. It is important in the gut for the production of prostaglandins, which inhibit gastric secretion. It can be induced in monocytes, macrophages and other cells. |
Immunogen | n/a |
Other Names | PTGS2, prostaglandin-endoperoxide synthase 2, prostaglandin G/H synthase, cyclooxygenase, COX-2, PHS-2, PGG/HS, PGHS-2, hCox-2 |
Gene, Accession # | Entrez: 29527, 5743; Uniprot: P35354, P35355 |
Catalog # | MA1-12236 |
Price | |
Order / More Info | COX2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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