| 产品详情 |
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| Antigenic Specificity | Phospho-IRS1 (Ser616) |
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| Clone | 26HCLC |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1 µg/mL, Immunofluorescence: 1 µg/mL, Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-IRS1 (Ser616) Antibody (26HCLC), ABfinity™ Rabbit Oligoclonal. Insulin receptor substrate 1 (IRS1) is encoded by the IRS1 gene located on chromosome 2. IRS1 is a member of the IRS family of adaptor molecules along with IRS 2 and 3, which play a critical role in insulin signaling. Insulin binding to its cognate receptor is followed by autophosphorylation on tyrosine residues and activation of the Insulin Receptor (IR). IRS1 contains pleckstrin homology (PH) and phosphotyrosine binding (PTB) domains at the N-terminus which directs IRS1 to IR. Phosphorylation of IRS1 on tyrosine residues is known to enhance insulin signaling while phosphorylation on Serine/Threonine residues can increase or decrease signaling. IRS1 interacts with |
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| Immunogen | n/a |
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| Other Names | IRS-1 |
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| Gene, Accession # | Entrez: 3667; Uniprot: P35568 |
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| Catalog # | 710780 |
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| Price | |
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| Order / More Info | Phospho-IRS1 (Ser616) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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