| 产品详情 |
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| Antigenic Specificity | Phospho-ITCH (Tyr420) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-ITCH (Tyr420) Polyclonal Antibody. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like protein family. This family of proteins are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. This encoded protein contains four tandem WW domains and a HECT domain. It can act as a transcriptional corepressor of p45/NFE2 and may participate in the regulation of immune responses by modifying Notch-mediated signaling. It is highly similar to the mouse Itch protein, which ha |
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| Immunogen | n/a |
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| Other Names | AIF4, AIP4, NAPP1, dJ468O1.1, E3 ubiquitin-protein ligase Itchy homolog, NFE2-associated polypeptide 1, atrophin-1 interacting protein 4, atrophin-1-interacting protein 4, dJ468O1.1 (atrophin 1 interacting protein 4 (AIP4)), itchy homolog E3 ubiquitin protein ligase, ubiquitin protein ligase ITCH |
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| Gene, Accession # | Entrez: 16396, 83737; Uniprot: Q8C863, Q96J02 |
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| Catalog # | PA5-37798 |
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| Price | |
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| Order / More Info | Phospho-ITCH (Tyr420) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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