| 产品详情 |
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| Antigenic Specificity | Phospho-JAK1 (Tyr1022) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-JAK1 (Tyr1022) Polyclonal Antibody. JAK1 (Janus kinase 1) belongs to the family of non-receptor Janus tyrosine kinases, which regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. Immunological stimuli, such as interferons and cytokines, induce recruitment of Stat transcription factors to cytokine receptor-associated JAK1. JAK1 then phosphorylates proximal Stat factors, which subsequently dimerize, translocate to the nucleus and bind to cis elements upstream of target gene promoters to regulate transcription. Upon ligand binding, JAK1 undergoes tyrosine phosphorylation and catalytic activation in an interdependent manner. Phosphorylation of tyrosine residues at posit |
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| Immunogen | n/a |
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| Other Names | AA960307, C130039L05Rik, JAK1A, JAK1B, Janus kinase 1, Janus kinase 1a. Entrez Gene ID: 3716 |
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| Gene, Accession # | Entrez: 16451, 3716, 84598; Uniprot: P23458, P52332 |
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| Catalog # | PA5-36657 |
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| Price | |
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| Order / More Info | Phospho-JAK1 (Tyr1022) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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