| 产品详情 |
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| Antigenic Specificity | Phospho-JAK3 (Tyr785) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-JAK3 (Tyr785) Polyclonal Antibody. Non-receptor tyrosine kinase involved in various processes such as cell growth, development, or differentiation. Mediates essential signaling events in both innate and adaptive immunity and plays a crucial role in hematopoiesis during T-cells development. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors sharing the common subunit gamma such as IL2R, IL4R, IL7R, IL9R, IL15R and IL21R. Following ligand binding to cell surface receptors, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins. Subsequently, phosphorylates the STATs proteins once they are recruited to the recepto |
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| Immunogen | n/a |
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| Other Names | JAK3; Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK |
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| Gene, Accession # | Entrez: 3718; Uniprot: P52333 |
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| Catalog # | PA5-40264 |
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| Price | |
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| Order / More Info | Phospho-JAK3 (Tyr785) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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