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Antigenic Specificity | Phospho-JAK1 (Tyr1022, Tyr1023) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-JAK1 (Tyr1022, Tyr1023) Polyclonal Antibody. Janus kinase 1 (JAK1), is a member of a new class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. JAK1 is involved in the interferon-alpha/beta and -gamma signal transduction pathways. The reciprocal interdependence between JAK1 and TYK2 activities in the interferon-alpha pathway, and between JAK1 and JAK2 in the interferon-gamma |
Immunogen | n/a |
Other Names | EC 2.7.10.2, JAK-1, JAK1, JAK1A, Janus kinase 1, kinase Jak1 |
Gene, Accession # | Entrez: 16451, 3716; Uniprot: P23458, P52332 |
Catalog # | 44-422G |
Price | |
Order / More Info | Phospho-JAK1 (Tyr1022, Tyr1023) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 12438594, 14701802, 15078941, 15522878, 15601754, 15611843, 15644867, 15767445, 17264307, 18084294, 19734231, 20167604, 20816854, 21976712, 22347506 |
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