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| Antigenic Specificity | Phospho-JIP1 (Thr103) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-JIP1 (Thr103) Polyclonal Antibody. The protein encoded by this gene is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibi |
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| Immunogen | n/a |
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| Other Names | IB1, JIP-1, JIP1, PRKM8IP, C-Jun-amino-terminal kinase-interacting protein 1, IB-1, JNK MAP kinase scaffold protein 1, JNK-interacting protein 1, PRKM8 interacting protein, islet-brain 1 |
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| Gene, Accession # | Entrez: 116457, 19099, 9479; Uniprot: Q9R237, Q9UQF2, Q9WVI9 |
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| Catalog # | PA5-38505 |
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| Price | |
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| Order / More Info | Phospho-JIP1 (Thr103) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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