产品详情 |
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Antigenic Specificity | GAS2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:20-1:50 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GAS2 Polyclonal Antibody. Gas2 is a 313 amino acid protein encoded by the human gene GAS2. Gas2 is thought to play a role in apoptosis by acting as a cell death substrate for caspases. Gas2, a component of the microfilament system, is cleaved by a caspase (caspase-3 and caspase-7) at Asparagine 278 during apoptosis. The cleaved form resulting from this dramatically induces the rearrangement of the Actin cytoskeleton and causes potent changes in the shape of the affected cells. Gas2 is believed to also be involved in the membrane ruffling process. During the G0-G1 transition phase Gas2 can be found phosphorylated on its serine residues. Gas2 is a cytoskeleton and peripheral membrane protein that co-localizes with Actin fibers at the cell bor |
Immunogen | n/a |
Other Names | GAS 2, GAS-2, Gas2, GAS2, Growth arrest specific 2, Growth arrest specific protein 2, Growth arrest-specific protein 2 |
Gene, Accession # | Entrez: 2620; Uniprot: O43903 |
Catalog # | PA5-63627 |
Price | |
Order / More Info | GAS2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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