| 产品详情 |
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| Antigenic Specificity | CD210 (IL-10R) |
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| Clone | 1B1.3a |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG1 |
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| Format | unconjugated, functional grade |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Functional Assay: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD210 (IL-10R) Monoclonal Antibody (1B1.3a), Functional Grade, eBioscience™. The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. |
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| Immunogen | n/a |
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| Other Names | CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2, CD210 |
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| Gene, Accession # | Entrez: 16154; Uniprot: Q61727 |
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| Catalog # | 16-2101-85 |
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| Price | |
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| Order / More Info | CD210 (IL-10R) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 21723158, 23772040 |
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