产品详情 |
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Antigenic Specificity | CD215 (IL-15Ra) |
Clone | eBioJM7A4 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.5 µg/test, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD215 (IL-15Ra) Monoclonal Antibody (eBioJM7A4), eBioscience™. Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding. Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits. IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2. |
Immunogen | n/a |
Other Names | IL-15RA, Interleukin-15 receptor subunit alpha, IL15RA, CD215 |
Gene, Accession # | Entrez: 3601; Uniprot: Q13261 |
Catalog # | 14-7159-82 |
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Order / More Info | CD215 (IL-15Ra) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 21270236 |
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