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Antigenic Specificity | CD217 (IL-17Ra) |
Clone | 424LTS |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | PerCP-eFluor 710 conjugate |
Size | 100 Tests |
Concentration | n/a |
Applications | Flow Cytometry: 5 µL (0.5 µg)/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD217 (IL-17Ra) Monoclonal Antibody (424LTS), PerCP-eFluor 710, eBioscience™. Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F. IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections. |
Immunogen | n/a |
Other Names | interleukin 17 receptor A; AW538159; Cdw217; IL17r; VDw217; interleukin 17 receptor |
Gene, Accession # | Entrez: 23765; Uniprot: Q96F46 |
Catalog # | 46-7917-42 |
Price | |
Order / More Info | CD217 (IL-17Ra) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |