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| Antigenic Specificity | CD217 (IL-17Ra) |
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| Clone | J10MBS |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 100 Tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 5 µL (0.25 µg)/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD217 (IL-17Ra) Monoclonal Antibody (J10MBS), PE, eBioscience™. Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F. IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections. |
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| Immunogen | n/a |
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| Other Names | interleukin 17 receptor A; AW538159; Cdw217; IL17r; VDw217; interleukin 17 receptor |
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| Gene, Accession # | Entrez: 23765; Uniprot: Q96F46 |
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| Catalog # | 12-7517-42 |
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| Price | |
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| Order / More Info | CD217 (IL-17Ra) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 21350122, 21530487 |
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