| 产品详情 |
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| Antigenic Specificity | NALP11 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:50-1:200, Western Blot: 0.4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NALP11 Polyclonal Antibody. NALP11 is a 1033 amino acid containing cytoplasmic protein belonging to the NLRP family with a DAPIN domain, six LRR (leucine-rich) repeats and a NACHT domain. Reports suggest that it is a short NALP involved in inflammation potential. NALP proteins are implicated in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes. The DAPIN domain is necessary and sufficient for suppression of NF-kappa B activation induced by TNF and for inducing IL-1B secretion in collaboration with Caspase-1. It is involved in interaction with PYCARD. |
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| Immunogen | n/a |
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| Other Names | CLR19.6, NALP11, NOD17, PAN10, PYPAF6, PYPAF7; NACHT, LRR and PYD containing protein 11; NACHT, LRR and PYD domains-containing protein 11; NACHT, leucine rich repeat and PYD containing 11; PAAD- and NACHT-containing protein 10; PAAD- and NACHT-containing protein 10B; PAAD-and NACHT domain-containing protein 10; PYRIN-containing APAF1-like protein 6; nucleotide-binding oligomerization domain protein 17; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 11 |
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| Gene, Accession # | Entrez: 204801; Uniprot: P59045 |
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| Catalog # | PA5-61235 |
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| Price | |
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| Order / More Info | NALP11 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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