| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | NALP4 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 50 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry (Paraffin): 1:1000-1:5000, Immunoprecipitation: 1:50-1:200, Western Blot: 1:1000-1:2000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | NALP4 Polyclonal Antibody. NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP4, also known as PYRIN-containing APAF1-like protein 4, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. In transfected 293 cells, NALP4 suppressed NF-kappa-B induction by TNF-a and IL-1-b, suggesting NALP4 operates at a point of convergence in these two signaling pathways. NALP4 also suppressed NF-kappa-B induction resulting from overexpression of several adapter proteins and protein kinases involved in these pathways, including TR |
|---|
| Immunogen | n/a |
|---|
| Other Names | CLR19.5, CT58, NALP4, PAN2, PYPAF4, RNH2; NACHT, LRR and PYD containing protein 4; NACHT, LRR and PYD domains-containing protein 4; NACHT, leucine rich repeat and PYD containing 4; PAAD and NACHT-containing protein 2; PYRIN and NACHT-containing protein 2; PYRIN-containing APAF1-like protein 4; cancer/testis antigen 58; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 4; ribonuclease inhibitor 2 |
|---|
| Gene, Accession # | Entrez: 147945, 446099; Uniprot: Q66X19, Q96MN2 |
|---|
| Catalog # | PA5-72910 |
|---|
| Price | |
|---|
| Order / More Info | NALP4 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|