产品详情 |
Edit |   |
Antigenic Specificity | NALP6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry: 1:50-1:200 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NALP6 Polyclonal Antibody. NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP6, also known as PYPAF5, is highly expressed in granulocytes and T cells and co-localizes with the PYRIN-CARD protein ASC. Co-expression of NALP6 with ASC results in a synergistic activation of NF-kappa-B and activated caspase-1-dependent cytokine processing, suggesting that NALP6 functions in immune cells to coordinate the transduction of pro-inflammatory signals. |
Immunogen | n/a |
Other Names | CLR11.4, NALP6, PAN3, PYPAF5; NACHT, LRR and PYD containing protein 6; NACHT, LRR and PYD domains-containing protein 6; NACHT, leucine rich repeat and PYD containing 6; PYRIN-containing APAF1-like protein 5; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 6 |
Gene, Accession # | Entrez: 171389; Uniprot: P59044 |
Catalog # | PA5-61758 |
Price | |
Order / More Info | NALP6 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
|
|