产品详情 |
Edit |   |
Antigenic Specificity | NAMPT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | chicken, human, mouse, nonhuman primate, rat |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:1000-1:5000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NAMPT Polyclonal Antibody. NAMPT is a 491 amino acid adipokine belonging to the NAPRTase family. It promotes angiogenesis via activation of the mitogen-activated protein kinase ERK-dependent pathway, is upregulated in neutrophils by IL-1beta, and functions as a novel inhibitor of apoptosis in response to a variety of inflammatory stimuli. It acts as a regulator of NAD+-dependent reactions in smooth muscle cells (SMCs) and in the pathogenesis of type 2 diabetes mellitus. NAMPT plays a role in insulin resistance and markers of hyperandrogenism in lean PCOS patients. It is a longevity protein that can add stress-resistant life to human smooth muscle cells by optimizing SIRT1-mediated p53 degradation. The expression level of NAMPT is high in vi |
Immunogen | n/a |
Other Names | 1110035O14Rik, PBEF, PBEF1, VF, VISFATIN, NAmPRTase, pre-B cell-enhancing factor, pre-B-cell colony enhancing factor 1, pre-B-cell colony-enhancing factor 1 |
Gene, Accession # | Entrez: 10135, 297508, 417707, 59027; Uniprot: P43490, Q80Z29, Q99KQ4 |
Catalog # | PA5-23198 |
Price | |
Order / More Info | NAMPT Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 27208486 |
产品资料 |
|
|