产品详情 |
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Antigenic Specificity | Nanog |
Clone | hNanog.2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Paraffin): 20 µg/mL, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nanog Monoclonal Antibody (hNanog.2), eBioscience™. NANOG (Nanog homeobox) is a divergent homeodomain protein that directs pluripotency and differentiation of undifferentiated embryonic stem cells. NANOG mRNA is present in pluripotent mouse and human cell lines, and absent from differentiated cells. Human NANOG protein shares 52% overall amino acid identity with the mouse protein, and 85% identity in the homeodomain. Human NANOG maps to gene locus 12p13.31, while the mouse NANOG maps to gene loci 6 F2. Murine embryonic NANOG expression is detected in the inner cell mass of the blastocyst. Research studies have shown that high levels of human NANOG expression in the undifferentiated N-Tera embryonal carcinoma cell line. Further, NANOG |
Immunogen | n/a |
Other Names | Nanog Homeobox; Homeobox Transcription Factor Nanog; FLJ12581 |
Gene, Accession # | Entrez: 79923; Uniprot: Q9H9S0 |
Catalog # | 14-5768-80 |
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Order / More Info | Nanog Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 20539761, 24598770, 25888366, 27191603, 28241084 |
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