产品详情 |
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Antigenic Specificity | PYGO2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | ChIP assay: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunofluorescence: Assay-dependent, Immunohistochemistry (Paraffin): 1:100-1:1000, Immunoprecipitation: Assay Dependent, Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PYGO2 Polyclonal Antibody. ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Is required but not sufficient to confer resistance against the lethal effects of reactive nitrogen intermediates (RNI), antimicrobial molecules produced by activated macrophages and other cell types. |
Immunogen | n/a |
Other Names | 1190004M21Rik, mpygo2, pygopus homolog 2 |
Gene, Accession # | Entrez: 68911, 90780; Uniprot: Q9BRQ0 |
Catalog # | PA5-31553 |
Price | |
Order / More Info | PYGO2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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