产品详情 |
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Antigenic Specificity | PYK2 |
Clone | 5E2D5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1/200 - 1/1000, Western Blot: 1/500 - 1/2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PYK2 Monoclonal Antibody (5E2D5). This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GT |
Immunogen | n/a |
Other Names | PKB; PTK; CAKB; FAK2; FRNK; PYK2; PTK2B |
Gene, Accession # | Entrez: 2185; Uniprot: Q14289 |
Catalog # | MA5-15407 |
Price | |
Order / More Info | PYK2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 28202937 |
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