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| Antigenic Specificity | Pyruvate Carboxylase |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Western Blot: 1:100 - 1:250 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Pyruvate Carboxylase Polyclonal Antibody. Pyruvate Carboxylase requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. |
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| Immunogen | n/a |
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| Other Names | PCB; pyruvate carboxylase; mitochondrial; pyruvic carboxylase |
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| Gene, Accession # | Entrez: 5091; Uniprot: P11498 |
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| Catalog # | PA5-66203 |
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| Price | |
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| Order / More Info | Pyruvate Carboxylase Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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