产品详情 |
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Antigenic Specificity | PZR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:1,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PZR Polyclonal Antibody. Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility. |
Immunogen | n/a |
Other Names | FLJ21047, immunoglobulin family transmembrane protein, MPZL1b, myelin protein zero-like 1, protein zero related, protein zero-related, PZR, PZR1b, PZRa, PZRb |
Gene, Accession # | Entrez: 9019; Uniprot: O95297 |
Catalog # | A304-411A-M |
Price | |
Order / More Info | PZR Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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