Edit |   |
Antigenic Specificity | TADA3L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 400 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TADA3L Polyclonal Antibody. Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have bee |
Immunogen | n/a |
Other Names | TADA3; ADA3; TADA3L; Transcriptional adapter 3; ADA3 homolog; STAF54; Transcriptional adapter 3-like |
Gene, Accession # | Entrez: 10474; Uniprot: O75528 |
Catalog # | PA5-35154 |
Price | |
Order / More Info | TADA3L Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |