| 产品详情 |
| Edit |   |
|---|
| Product Name | CD80, BioAssay™ ELISA Kit (Rat) (Cluster of Differentiation 80, B7-1) |
|---|
| Description | The protein CD80 (Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7-1. The cDNA for B7-1 predicts a type I membrane protein, i.e., one synthesized with a signal peptide that is cleaved upon translocation across the endoplasmic membrane. The protein is predicted to contain 2 extracellular domains structurally similar to those of Ig, a hydrophobic transmembrane region, and a short cytoplasmic domain.The CD80 and CD86 genes encode B7-1 and B7-2, respectively, which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. B7-1 and B7-2 provide a costimulatory signal to T cells by interacting with CD28 and CTLA4. Sample Type: Cell culture supernates and serum. Intended Use: For quantitative detection of rat CD80 in cell culture supernates and serum. Sensitivity: <2pg/ml Range: 62.5-4000pg/ |
|---|
| Size | 96 tests |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | Gene ID: 25408, SwissProt: O35187 |
|---|
| Catalog # | 352776 |
|---|
| Price | |
|---|
| Order / More Info | CD80, BioAssay™ ELISA Kit (Rat) (Cluster of Differentiation 80, B7-1) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|