产品详情 |
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Antigenic Specificity | PML |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 400 µL |
Concentration | n/a |
Applications | Flow Cytometry: 1:10-1:50, Immunocytochemistry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PML Polyclonal Antibody. PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). |
Immunogen | n/a |
Other Names | Tripartite motif-containing protein 19; RING finger protein 71; MYL; RNF71; TRIM19 |
Gene, Accession # | Entrez: 5371; Uniprot: P29590 |
Catalog # | PA5-12185 |
Price | |
Order / More Info | PML Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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