| 产品详情 |
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| Antigenic Specificity | PMSCL1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | chicken, human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunofluorescence: 1:100, Immunohistochemistry (Paraffin): 1:50-1:100, Immunoprecipitation: Assay-Dependent, Western Blot: 1:5000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PMSCL1 Polyclonal Antibody. Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination |
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| Immunogen | n/a |
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| Other Names | EXOSC9; exosome component 9; PM/Scl-75; PMSCL1; RRP45; Rrp45p; p5; p6; P75 polymyositis-scleroderma overlap syndrome associated autoantigen; PMSCL autoantigen, 75kD; autoantigen PM/Scl 1; polymyositis/scleroderma autoantigen 1 (75kD); polymyositis/scleroderma autoantigen 1, 75kDa |
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| Gene, Accession # | Entrez: 50911, 5393, 619530; Uniprot: Q06265, Q9JHI7 |
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| Catalog # | PA5-72959 |
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| Price | |
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| Order / More Info | PMSCL1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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