| 产品详情 |
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| Antigenic Specificity | STUB1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | STUB1 Polyclonal Antibody. A recently identified protein, termed carboxyl terminus of hsc70-interacting protein (CHIP), has been shown to interact both with the constitutive form of hsc70 and the stress inducible form, hsp70. This novel 35 kDa cytoplasmic protein has been shown to be highly expressed in striated muscle in vivo. Additional studies have shown that this protein is expressed over a broad range of cultured tissues. Through immunoprecipitation experiments, CHIP has been shown to directly bind to the carboxyl terminus of hsc70 and hsp70 where it decreases ATPase activity and reduces overall chaperone efficiency. CHIP has also been identified as an important protein in the ubiquitin-proteasome system. CHIP contains a U-box domain a |
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| Immunogen | n/a |
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| Other Names | Carboxyl Terminus of Hsc70-Interacting Protein |
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| Gene, Accession # | Entrez: 10273, 56424; Uniprot: Q9UNE7, Q9WUD1 |
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| Catalog # | PA1-015 |
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| Price | |
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| Order / More Info | STUB1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10330192, 14612456, 16037132, 17324930, 18955503, 19953350, 20348093, 22128174 |
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