产品详情 |
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Antigenic Specificity | Tyro3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunoprecipitation: 5-20 µg/mg lysate, Western Blot: 1:5,000-1:20,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tyro3 Polyclonal Antibody. TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. It regulates many physiological processes including cell survival, migration, and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by a ligand, TYRO3 plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation, and cytoskeleton reorganization. |
Immunogen | n/a |
Other Names | Tyrosine-protein kinase SKY, BYK, DTK, RSE; TYRO3 |
Gene, Accession # | Entrez: 7301; Uniprot: Q06418 |
Catalog # | A300-242A |
Price | |
Order / More Info | Tyro3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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