| 产品详情 |
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| Antigenic Specificity | TYROBP |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TYROBP Polyclonal Antibody. This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative rec |
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| Immunogen | n/a |
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| Other Names | DAP12, KARAP, PLOSL |
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| Gene, Accession # | Entrez: 7305; Uniprot: O43914 |
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| Catalog # | PA1-29027 |
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| Price | |
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| Order / More Info | TYROBP Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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