| 产品详情 |
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| Antigenic Specificity | TYROBP |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:10-1:50, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TYROBP Polyclonal Antibody. TYROBP encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative recept |
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| Immunogen | n/a |
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| Other Names | DAP12, KARAP, PLOSL, DNAX-activation protein 12, KAR-associated protein, TYRO protein tyrosine kinase-binding protein, killer activating receptor associated protein, killer-activating receptor-associated protein |
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| Gene, Accession # | Entrez: 7305; Uniprot: O43914 |
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| Catalog # | PA5-26861 |
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| Price | |
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| Order / More Info | TYROBP Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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