| 产品详情 |
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| Antigenic Specificity | TYROBP |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-4 µg/mL protein lysate, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TYROBP Polyclonal Antibody. DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans. |
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| Immunogen | n/a |
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| Other Names | TYROBP, KARAP, PLOSL |
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| Gene, Accession # | Entrez: 22177, 7305; Uniprot: O43914, O54885 |
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| Catalog # | PA1-12701 |
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| Price | |
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| Order / More Info | TYROBP Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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