产品详情 |
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Antigenic Specificity | Tyrosinase |
Clone | T311 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2a |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Immunohistochemistry (Paraffin): 2-4 µg/mL, Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tyrosinase Monoclonal Antibody (T311). Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. |
Immunogen | n/a |
Other Names | LB24-AB, SK29-AB, monophenol monooxygenase, tumor rejection antigen AB, tyrosinase |
Gene, Accession # | Entrez: 22173, 7299; Uniprot: P11344 , P14679 |
Catalog # | MA5-14177 |
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Order / More Info | Tyrosinase Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 11930111, 12472287, 12649746, 15269149, 15278367, 15695408, 16260696, 17318568, 17667527, 17913955, 19086131, 19241195, 19590421, 19780816, 20375743, 20952280, 21317285, 21673904, 21750202, 22103332, 22703822, 26387540 |
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