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Antigenic Specificity | Tyrosinase |
Clone | T311 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2a, kappa |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunohistochemistry: Assay Dependent, Western Blot: 2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tyrosinase Monoclonal Antibody (T311). Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. |
Immunogen | n/a |
Other Names | CMM8, OCA1A, OCAIA, SHEP3, LB24-AB, SK29-AB, monophenol monooxygenase, tumor rejection antigen AB, tyrosinase |
Gene, Accession # | Entrez: 22173, 7299; Uniprot: P11344, P14679 |
Catalog # | 35-6000 |
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Order / More Info | Tyrosinase Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 18344451, 21750202, 22467596, 23757003, 24991188, 7667256 |
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