| 产品详情 |
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| Antigenic Specificity | Tyrosine Hydroxylase |
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| Clone | 185 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 50 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent, Immunohistochemistry (Frozen): 1:20-1:40, Western Blot: 1:25-1:50 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Tyrosine Hydroxylase Monoclonal Antibody (185). Tyrosine hydroxylase (TH) is an enzyme involved in the synthesis of catecholamine neurotransmitters dopamine, epinephrine, and norepinephrine. In all species, catecholamine synthesis is regulated by the interaction of TH with a cofactor, tetrahydrobiopterin (BH4). BH4 binds to the TH catalytic domain, resulting in enzymatic activity. Unlike TH in non-primate species, four human TH mRNA splice variants (hTH1-hTH4) have been isolated. These variants are identical in their catalytic domain, but differ in their N-terminal, regulatory domains. TH is also responsible for the conversion of L-tyrosine to L-dopa. TH plays a key role in the physiology of adrenergic neurons. The role of TH in the synthes |
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| Immunogen | n/a |
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| Other Names | TH, TYH antibody, Tyrosine 3 monooxygenase antibody |
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| Gene, Accession # | Entrez: 21823, 25085, 7054; Uniprot: P04177, P07101, P24529 |
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| Catalog # | MA1-24654 |
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| Price | |
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| Order / More Info | Tyrosine Hydroxylase Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 19303727, 21347406, 22934193, 24491944, 24503446 |
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