Edit |   |
Antigenic Specificity | U2AF1L4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | U2AF1L4 Polyclonal Antibody. RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site. |
Immunogen | n/a |
Other Names | U2AF1L3V1; U2AF1L3; U2 small nuclear RNA auxiliary factor 1-like 4; U2AF1RS3; U2af26; U2AF1-RS3 |
Gene, Accession # | Entrez: 199746; Uniprot: Q8WU68 |
Catalog # | PA5-66408 |
Price | |
Order / More Info | U2AF1L4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |