产品详情 |
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Antigenic Specificity | WT1 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | peptide-ELISA: 1:32000, Western Blot: 1-3 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | WT1 Polyclonal Antibody. This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence |
Immunogen | n/a |
Other Names | WT1; Wilms tumor 1; GUD; WAGR; WIT-2; WT33 |
Gene, Accession # | Entrez: 7490; Uniprot: P19544 |
Catalog # | PA5-18548 |
Price | |
Order / More Info | WT1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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