| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | WTAP |
|---|
| Clone | OTI6H3 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100 µl |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | WTAP Monoclonal Antibody (OTI6H3). Wilms' tumor (WT) is an embryonal malignancy of the kidney that affects 1 in 10,000 infants and is observed in both sporadic and inherited forms. The Wilms' tumor protein (WT1) binds the DNA sequence GCGGGGGCG, a recognition element common to the early growth response (Egr) family of Zn2+ finger transcriptional activators, and functions as a transcriptional repressor. WTAP (Wilms tumor 1-associating protein) is a ubiquitously expressed nuclear protein that interacts with WT1 and may be involved in regulating mRNA splicing. WTAP is found in nuclear speckles, where it regulates the G2/M cell cycle transition by binding to the 3' UTR of cyclin A2, thus enhancing its stability. Additionally, WTAP inhibits expr |
|---|
| Immunogen | n/a |
|---|
| Other Names | PNAS-132, WT1-associated protein, Wilms' tumour 1-associating protein, female-lethal(2)D homolog, hFL(2)D, pre-mRNA-splicing regulator WTAP, putative pre-mRNA splicing regulator female-lethal(2D), wilms tumor 1-associating protein |
|---|
| Gene, Accession # | Entrez: 9589; Uniprot: Q15007 |
|---|
| Catalog # | MA5-26971 |
|---|
| Price | |
|---|
| Order / More Info | WTAP Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|