产品详情 |
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Antigenic Specificity | WTIP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 400 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | WTIP Polyclonal Antibody. Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing. Negatively regulates Hippo signaling pathway and antagonizes phosphorylation of YAP1. Acts as a transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadherin transcription. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. In podocytes, may play |
Immunogen | n/a |
Other Names | Wilms tumor protein 1-interacting protein, WT1-interacting protein, WTIP |
Gene, Accession # | Entrez: 126374; Uniprot: A6NIX2 |
Catalog # | PA5-48292 |
Price | |
Order / More Info | WTIP Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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