| 产品详情 |
| Edit |   |
|---|
| Product Name | ESI-09 |
|---|
| Description | Purity >95%. Exchange protein activated by cAMP (Epac) proteins mediate cAMP signaling independent of protein kinase A (PKA). ESI-09 is an inhibitor of Epac1 and Epac2 with IC50 values of 3.2 and 1.4 µM, respectively. It shows no activity against PKA at concentrations as high as 25 µM. ESI-09 has been shown to block Akt phosphorylation and insulin secretion in pancreatic Beta cells, as well as to block the migration of AsPC-1 and PANC-1 pancreatic cancer cells in vitro . |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | a-[2-(3-chlorophenyl)hydrazinylidene]-5-(1,1-dimethylethyl)-Beta-oxo-3-isoxazolepropanenitrile |
|---|
| Gene, Accession, CAS # | CAS: 263707-16-0 |
|---|
| Catalog # | LS-H7706 |
|---|
| Price | |
|---|
| Order / More Info | ESI-09 from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|