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Product Name | FGF-9 (AA 3-208), (Ser34Asn-Mutant) (Active) protein |
Description | Fibroblast Growth Factor-9 (FGF-9) is a pleiotropic cytokine and belongs to the heparin-binding FGF family. Like other members in the family, FGF-9 resembles a beta-trefoil structure. FGF-9 undergoes reversible dimerization, a common characteristic shared by its subfamily members, FGF-16 and FGF-20. The mutations involved in the homodimerization also affect the affinity for heparin, binding to FGF receptors, and biological activity. In vivo, FGF-9 is expressed in limb buds, the developing skeleton, and in the intestines during late stage embryogenesis. FGF-9 is essential for the development of heart, lung, kidney, cecum, and testes, and the reduction of FGF-9 level leads to premature differentiation. FGF-9 also works along with Bone Morphogenetic Protein-7 (BMP-7) to promote the survival of nephron progenitors.Recombinant mouse Fibroblast Growth Factor (rmFGF-9) produced in E. coli is a single non-glycosylated polypeptide chain containing 207 amino acids. A fully biologically active molecule, rmFGF-9 has a molecular mass of 23.4 kDa analyzed by reducing SDS-PAGE. Synonyms: Growth Factor-9, GAF (Glia-activating factor), HBGF-9 |
Size | 10 µg |
Concentration | n/a |
Applications | n/a |
Other Names | Eks|FGF-9|GAF|HBFG-9|HBGF-9|SYNS3|XFGF-9|fgf9-A |
Gene, Accession, CAS # | Gene ID: 14180 |
Catalog # | ABIN2017839 |
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Order / More Info | FGF-9 (AA 3-208), (Ser34Asn-Mutant) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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