| 产品详情 |
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| Antigenic Specificity | APRIL |
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| Clone | Sacha-1 |
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| Host Species | Rat |
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| Reactive Species | human, mouse |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1 µg/mL, Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry: Assay-dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APRIL Monoclonal Antibody (Sacha-1). Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer. |
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| Immunogen | n/a |
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| Other Names | APRIL, CD256, TALL2, TRDL-1, UNQ383/PRO715, TNFSF13 |
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| Gene, Accession # | Entrez: 69583, 8741; Uniprot: O75888, Q9D777 |
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| Catalog # | MA1-21169 |
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| Price | |
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| Order / More Info | APRIL Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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