产品详情 |
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Antigenic Specificity | APRIL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Western Blot: 5-10 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | APRIL Polyclonal Antibody. Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for a proliferation-inducing ligand), TALL-2 (for TNF- and ApoL-related Leukocyte-expressed Ligand 2), and TRDL-1-a (for TNF related death ligand 1-a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kappa-B, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer. |
Immunogen | n/a |
Other Names | APRIL, CD256, TALL2, TRDL-1, UNQ383/PRO715, TNFSF13 |
Gene, Accession # | Entrez: 8741; Uniprot: O75888 |
Catalog # | PA5-19942 |
Price | |
Order / More Info | APRIL Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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