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| Product Name | Pyruvate Dehydrogenase Kinase, Isozyme 1 (PDK1) (AA 29-436) protein (His tag) |
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| Description | PDK1 takes part in the regulation of enzymatic activity of mammalian pyruvate dehydrogenase which is part of a mitochondrial multienzyme complex to catalyze the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. PDK1 inhibits glioblastoma growth. PDK1 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the e1 alpha subunit, therefore contributing to the regulation of glucose metabolism. PDK1 kinase activity is negatively regulated by binding to 14-3-3 Synonyms: Pyruvate dehydrogenase kinase isoform 1, PDK1, Pyruvate dehydrogenase (lipoamide) kinase isozyme 1 mitochondrial |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | B830012B01|D530020C15Rik|si:zfos-979f1.3 |
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| Gene, Accession, CAS # | Gene ID: 5163 |
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| Catalog # | ABIN806408 |
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| Order / More Info | Pyruvate Dehydrogenase Kinase, Isozyme 1 (PDK1) (AA 29-436) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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