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| Product Name | CAL-101 (GS-1101) |
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| Description | Purity >98% by HPLC. CAL-101 is a cell-permeable inhibitor of the PI3K catalytic subunit p110d (IC50 = 2.5 nM) that displays 40- to 300-fold selectivity against other PI3K class I enzymes (IC50s = 820, 565, and 89 nM for p110a, Beta, and Gamma, respectively). It has also been shown to inhibit the chemotaxis of chronic lymphocytic leukemia cells and to downregulate the secretion of chemokines triggered by B-cell receptor signaling. A potent PI3K p110d inhibitor. (Biochemical) |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone, Idealisib |
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| Gene, Accession, CAS # | CAS: 870281-82-6 |
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| Catalog # | LS-H3179 |
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| Order / More Info | CAL-101 (GS-1101) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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