产品详情 |
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Product Name | EUK 118 |
Description | Purity >95%. EUK 8 and EUK 134 are synthetic catalytic scavengers of reactive oxygen species with superoxide dismutase (SOD) and catalase mimetic activity. EUK 118 is a structural analog of EUK 8 and EUK 134 with significantly reduced activity. EUK 118 exhibits a catalase activity of 35 µM O2 formed/minute from 10 mM hydrogen peroxide, which is more than four times lower that that observed for EUK 8 under the same conditions. Superoxide-mediated reduction of an electron acceptor (i.e., SOD mimetic activity) was inhibited by EUK 118 and EUK 8 with IC50 values of 2 and 0.7 µM, respectively. EUK 118 did not protect human dermal fibroblasts against hydrogen peroxide-induced cell death. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | (acetato-?O)[[2,2'-[1,2-ethanediylbis[(nitrilo-?N)methylidyne]]bis [3,5-dimethoxyphenolato-?O]](2-)]-manganese |
Gene, Accession, CAS # | CAS: 186299-34-3 |
Catalog # | LS-H7734 |
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Order / More Info | EUK 118 from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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