| 产品详情 |
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| Antigenic Specificity | OVCA2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Western Blot: 1:250 - 1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | OVCA2 Polyclonal Antibody. Chromosome 17 is a hotspot for chromosomal aberrations in breast and ovarian cancer. Candidate oncogenes and tumor suppressors located on this chromosome include OVCA1 and OVCA2, p53, BRCA1, HER2/neu and others. OVCA1 and 2 map to a highly conserved region on human chromosome 17p13.3 that is deleted in 80% of ovarian cancers and shows frequent loss of heterozygosity in breast cancers . OVCA1 is induced by BRCA1 and is closely linked to p53, a well-known tumor suppressor gene. The close linkage of OVCA1 and p53 suggests that coordinated loss of the two genes may lead to ovarian, breast and other tumor types. |
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| Immunogen | n/a |
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| Other Names | esterase OVCA2; candidate tumor suppressor in ovarian cancer 2; ovarian cancer gene-2 protein; ovarian cancer-associated gene 2 protein; ovarian tumor suppressor candidate 2 |
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| Gene, Accession # | Entrez: 124641; Uniprot: Q8WZ82 |
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| Catalog # | PA5-66228 |
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| Price | |
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| Order / More Info | OVCA2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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