| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Human Alpha N-terminal protein methyltransferase 1A (METTL11A) |
|---|
| Description | Purity > 90% as determined by SDS-PAGE. MW: 41.4kDa. Full Length: 1-223aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1. |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | Alpha N-terminal protein methyltransferase 1AMethyltransferase-like protein 11AN-terminal R; CC1 methyltransferaseX-Pro-Lys N-terminal protein methyltransferase 1A; NTM1A |
|---|
| Gene, Accession, CAS # | NTMT1, UniProt: Q9BV86 |
|---|
| Catalog # | RPC23664 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Human Alpha N-terminal protein methyltransferase 1A (METTL11A) from BIOMATIK |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|