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| Product Name | Recombinant Human Voltage-gated potassium channel subunit beta-2 (KCNAB2) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 57kDa. Full Length: 1-367aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Cytoplasmic domain potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability. Promotes expression of the pore-forming alpha subunits at the cell mbrane, and thereby increases channel activity. Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore. Promotes KCNA4 channel closure. Modulates the functional properties of KCNA5. Enhances KCNB2 channel activity. Binds NADPH and has NADPH-dependent aldoketoreductase activity. Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal (in vitro). |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | K (+) channel subunit beta-2Kv-beta-2; hKvbeta2 |
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| Gene, Accession, CAS # | KCNAB2, UniProt: Q13303 |
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| Catalog # | RPC21551 |
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| Order / More Info | Recombinant Human Voltage-gated potassium channel subunit beta-2 (KCNAB2) from BIOMATIK |
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| Product Specific References | n/a |
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