| 产品详情 |
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| Product Name | GW 4869 dihydrocloride |
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| Description | Purity >90%. GW 4869 is a cell-permeable, non-competitive inhibitor of neutral sphingomyelinases (IC50 = 1 MM), but does not affect acid sphingomyelinase activity. It inhibits TNF-a-mediated sphingomyelin hydrolysis (100% inhibition at 20 MM) and TNF-a-induced cell death in MCF7 cells without interfering with activation of NF- Kappa B or glutathione depletion in response to TNF. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Dihydrochloride, 3,3'-(1,4-phenylene)bis[N-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-2-propenamide, GW554869A, GW69A |
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| Gene, Accession, CAS # | CAS: 6823-69-4 |
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| Catalog # | LS-H2992 |
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| Order / More Info | GW 4869 dihydrocloride from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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